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Description

Nucl Med Mol Imaging 48:106113

doi:10.1165/ajrcmb.23.3.f197

Alpha-synuclein binds with DA via polar amino acid threonine while MMP9 and UCHL1 bind through non-polar, aliphatic amino acids with DA

This process increases mitochondrial membrane permeability, leads to the loss of membrane potential, and triggers the release of pro-apoptotic factors [117]